I too have a Microsoft Natural Keyboard 4000. It is great keyboard but came with two initial flaws:
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The space bar makes an awful FLAK sound when clicked from the RHS (sounds normal from the left but who the hell clicks space with their left hand?). Fix: Use it for a few days and you get used to it
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GOD AWFUL F LOCK BUTTON that makes all the function keys do weird things if you press it accidentally. FIX: PULL THAT F#$%ER OUT. After the thousand time it did it, i yanked the button out and blu-tacked a appropriately cut piece of black plastic its place