I hate QWERTY. It was made to be inconvinient, and it really is. I'm Russian and spend much time at forums, where I use common Russian layout #1049;#1062;#1059;#1050;#1045;#1053;. It is arranged in such a way that most of the frequent letters are typed with the forefingers.
When I use QWERTY, howerver, I have to use my ring and pinky fingers a lot, which is not really comfortable. And even worse, I have to use my left hand more than the right hand. It's not problem that it is left, I play guitar besides programming, so fingers on both of my hands are quite agile. The problem is that it is slower than typing with two hands at a time. That's why I try some weird positions of my hands to type quick and use CTRL + Space in NetBeans a lot.
Why can't the keyboard manufacturers make keyboards with a better layout, I wonder? I don't believe that it would be so difficult to switch to another layout if it's really comfortable. By the way, I don't find Dvorak much better as it still suffers form the same problem: frequent letters like A, O, E vowels on the outskirts of keyboard.