Isn’t Titan X faster than the 980 Ti, albeit not twice as fast as the price would suggest? 
As I just switched to a high-dpi laptop using 200% dpi-scaling I’ve so far discovered at least three applications I use almost daily that have serious issues.
Zoomplayer
My favourite desktop media player, mostly because the easy playlist control and the ability to fullscreen it to another monitor (like when holding presentations) without having to manually move the window first. Sadly it doesn’t scale any of its interface, it’s super-tiny and barely usable.
Windows 8.1 Media Player 12
Alright, so how do I play some media at bars and during conferences without Zoomplayer? Queue Media Player, but wait - the playlist (view list) doesn’t handle high dpi correctly! You will get a list that is around 5 characters wide at its widest setting making it impossible to see what is going on. This really surprises me 
Some device driver dialogs
Using Vmix HD (which scales perfectly btw, great work on that!) when diving deep into device configuration dialogs you sometimes end up with a dropdown list or other element that on activation is re-positioned wrongly and at the non-scaled super-tiny size.
Traktor Pro 2.9 (latest version released just now)
Doesn’t support scaling at all so everything is super-tiny - but that’s not all, it also exhibits a bug which prevents maximizing or going fullscreen - it will only take up a quarter corner of your desktop. The only way to get it fullscreen is to disable scaling for it using the compatibility shims and then it’s simply too tiny to be usable. Using 125% scaling things work but it’s not enough in my case and the knobs and text (even with the program’s own text-size changed to max) is too tiny.
Windows 10 systray
In combination with my culture’s date format of choice (yyyy-MM-dd) and having the taskbar vertically to the side - the date will basically spill out of the systray area! It looks really shoddy and I had to manually widen the taskbar a bit from its usual minimum width. Windows 10 has all sorts of annoying quirks when using a vertical taskbar though…
I for one am looking forward to a 21:9 34" IPS monitor that supports G-Sync and handles at least 90Hz or more - there seems to be one such beast arriving any week now: http://www.144hzmonitors.com/monitors/acer-x34-xr341cka-has-a-g-sync-range-of-30-100hz/
The world of adaptive sync is coming, and I’m looking forward to once again watch screens and applications that doesn’t stutter, tear or generally misbehave from a motion standpoint - something that was lost when the analog CRT era ended (and the Amiga died, sad smiley). Hopefully anyway.
I wonder if an adaptive sync screen could sync to a C64’s awkward ~50.25Hz framerate which causes frame skips every x second on a 50Hz digital display or broadcast bus… and how good will, say, Youtube videos be, could we get automatic refresh rate sync with the video’s actual framerate so it doesn’t stutter anymore? That would be awesome, maybe decided on whatever window has focus. When the monitors can do 1000 Hz it might be a non-issue…